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342(6161):979-83
Smiles: CN1CCN(CC2=CC=C(C=C2C(F)(F)F)NC(=O)C2=CC(C#CC3=CN=C4NN=CC4=C3)=C(C)C=C2)CC1
Smiles: CC1(C)[C@@H]2CC[C@]3(C)[C@H](C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)[C@@]2(C)CC[C@@H]1O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O
CAS Number: 726169-73-9
Solubility: DMSO : 100 mg/mL (330
Erlotinib U-03012 342(6161):979-83Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor). Erlotinib HCl was approved. Erlotinib binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the
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