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BAY-57-1293 - CAS# 348086-71-5 size:10mg solid with IC50s of 7

SKU: 43955551347

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Description

with IC50s of 7

PubMed PMID: 22284361

86(3):194-9

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines

Molecular Weight: 375

BAY-57-1293 - CAS# 348086-71-5 size:10mg solid with IC50s of 7BAY 57 1293, CAS No. 348086 71 5, is a potent helicase primase inhibitor. BAY 57 1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57 1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound

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