Cariprazine Hydrochloride Catalog No.:M11217-2 Nilsson LA

Nilsson LA

Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305)

monohydrochloride (9CI)

CAS Number: 123441-03-2

32 mM) Ethanol 84 mg/mL (200

Cariprazine Hydrochloride Catalog No.:M11217-2 Nilsson LACariprazine, also known as RGH 188 and MP 214, is an antipsychotic drug received FDA approval on September 17, 2015. Cariprazine acts as a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. Action on the dopaminergic systems makes it also potentially useful as an add on therapy in major depressive disorder. Cariprazine is approved for schizophrenia and bipolar disorder. It has also been investigated as a potential