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HS-173 inhibits TGF-β-induced cell migration and invasion in pancreatic cancer cells
It binds to phospholipids in the cell membrane and inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production
) enhances the mean survival time of the tumor bearing Swiss albino mice
InChi: InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14
Cancer Chemother Pharmacol
Desloratadine Size:Solid 10 mg HS-173 inhibits TGF-β-induced cell migrationDesloratadine is a tricyclic H1 antihistamine that is used to treat allergies. It is an active metabolite of loratadine. Desloratadine is a selective H1 antihistamine which functions as an inverse agonist at the histamine H1 receptor; it is also an antagonist at all subtypes of the muscarinic acetylcholine receptors. It has a long lasting effect and in moderate and low doses. It exhibits only peripheral activity since it does not readily cross the
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