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APC 366 de-O-amido-C8-NH2 hydrochloride Anandamide is an endocannabinoid binding

SKU: 46078168309

4.1
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Description

Anandamide is an endocannabinoid binding both CB1R and CB2R

Formula: C8H10ClN3O

InChi: InChI=1S/C11H15BrClN

3R)-4-[[(2R)-1-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethylamino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]carbamate

Niga-ichigoside F1 has no effects on cell viability

APC 366 de-O-amido-C8-NH2 hydrochloride Anandamide is an endocannabinoid bindingAPC 366 is a selective and competitive inhibitor of tryptase [1, 2, 3]. After about 4 h of incubation with human tryptase, APC 366 showed an inhibitory potential with a Ki value of 530 nM and an IC50 value of 1400 240 nM . Tryptase is a mast cell serine protease. It had been implicated in the allergic asthma pathophysiology . It seemed that actions of tryptase were dependent on an intact catalytic site. APC 366 inhibited DNA synthesis and the

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