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Lopinavir-d8 0658 InChi: InChI=1S/C31H38N2O5/c1-20(2)32-31(34)30(22-10-8-7-9-11-22)33-15-14-23-18-28(37-5)29(38-6)19-24(23)25(33)16-21-12-13-26(35-3)27(17-21)36-4/h7-13

SKU: 46760871371

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Description

InChi: InChI=1S/C31H38N2O5/c1-20(2)32-31(34)30(22-10-8-7-9-11-22)33-15-14-23-18-28(37-5)29(38-6)19-24(23)25(33)16-21-12-13-26(35-3)27(17-21)36-4/h7-13

RSVA405 (1-3 μM

Smiles: O[C@H](CN1CCOCC1)CN1OC(=C(Cl)C1=O)C1C=CC=CC=1

InChi: InChI=1S/C47H72O17/c1-21-28(50)30(52)32(54)37(59-21)63-35-34(62-38-33(55)31(53)29(51)24(19-48)60-38)23(49)20-58-39(35)61-27-12-13-42(4)25(41(27

CAS Number: 242143-80-2

Lopinavir-d8 0658 InChi: InChI=1S/C31H38N2O5/c1-20(2)32-31(34)30(22-10-8-7-9-11-22)33-15-14-23-18-28(37-5)29(38-6)19-24(23)25(33)16-21-12-13-26(35-3)27(17-21)36-4/h7-13Lopinavir d8 (ABT 378 d8) is the deuterium labeled Lopinavir. Lopinavir (ABT 378) is a highly potent, selective peptidomimetic inhibitor of the HIV 1 protease, with Kis of 1. 3 to 3. 6 pM for wild type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV 1 thereby blocking its infectivity. Lopinavir is also a SARS CoV 3CLpro inhibitor with an IC50 of 14. 2 M. Product information CAS Number: 1224729 35 4 Molecular Weight: 636. 85

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