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(R)-FT671 e-1 3-dione unlike other third-generation dihydropyridine derived

SKU: 47535620424

4.8
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Description

unlike other third-generation dihydropyridine derived drugs

Blockade of endogenous proinflammatory cytokines ameliorates endothelial dysfunction in obese Zucker rats

It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch

MLN8054 induces DNA and tubulin staining of tumor tissue in nuclear and cell body area

which dues to the inhibition of phosphorylation of EGFR

(R)-FT671 e-1 3-dione unlike other third-generation dihydropyridine derived(R) FT671 is the R isomer of FT671. FT671 is a potent, non covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM. Product information CAS Number: 1959551 27 9 Molecular Weight: 533. 48 Formula: C24H23F4N7O3 Chemical Name: 5 ({1 [(3R) 4,4 difluoro 3 (3 fluoro 1H pyrazol 1 yl)butanoyl] 4 hydroxypiperidin 4 yl}methyl) 1 (4 fluorophenyl) 1H,4H,5H pyrazolo[3,4 d]pyrimidin 4 one Smiles:

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