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It increases the knock-in efficiency by two- to five-fold at different loci
KPT-185 is a selective and irreversible inhibitor of chromosome maintenance protein 1 (CRM1)
carbendazim also suppresses dynamic instability
Smiles: CC1C=CC2C(=CC=CC=2N2CCN(CCC3=CC(=CC=C3)N3CCNC3=O)CC2)N=1
This frees the amino terminal of the peptide
Fmoc-NH-PEG1-C2-acid 23768 It increases the knock-in efficiencyFmoc NH PEG1 C2 acid is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1654740 73 4 Molecular Weight: 355. 38 Formula: C20H21NO5 Chemical Name: 3 [2 ({[(9H fluoren 9 yl)methoxy]carbonyl}amino)ethoxy]propanoic acid Smiles: OC(=O)CCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21 InChiKey: LHBCOPWWQKLECJ UHFFFAOYSA N InChi: InChI=1S C20H21NO5 c22 19(23)9 11 25 12 10 21 20(24)26 13 18 16 7 3 1 5 14(16)15 6 2 4
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