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MCOPPB-trihydrochloride
in cells transfected with the empty plasmid which has no CYP1B1 gene and therefore cannot express CYP1B1 protein
30675-13-9
and shows no effect on SV40 luciferase reporter
(S)-Crizotinib is a useful chemical probe to further validate MTH1 as a promising novel class of anticancer target
Vinflunine tartrate Ivabradine Hydrochloride MCOPPB-trihydrochlorideVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.