JC-171 IN 3 3-H)propan-2-yl]pyrimidin-5-yl]-3

3-H)propan-2-yl]pyrimidin-5-yl]-3

7 microM) tyrosine kinases

1992 Sep-Oct

Smiles: NCCOCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

Formula: C15H21N3O6

JC-171 IN 3 3-H)propan-2-yl]pyrimidin-5-yl]-3JC 171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8. 45 M for inhibiting LPS ATP induced interleukin 1 (IL 1) release from J774A. 1 macrophages. Product information CAS Number: 2112809 98 8 Molecular Weight: 384. 83 Formula: C16H17ClN2O5S Chemical Name: 5 chloro N {2 [4 (hydroxysulfamoyl)phenyl]ethyl} 2 methoxybenzamide Smiles: COC1=CC=C(Cl)C=C1C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NO InChiKey: KQRQPMUPYDOTCA UHFFFAOYSA N InChi: InChI=1S