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339(1):228-37
(2005) J Pharmacol Exp Ther
Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor
After 28 days of Bardoxolone methyl administration
5-Furandione
ABT-751 - CAS# 141430-65-1 60163 339(1):228-37ABT 751, also known as E7010, CAS No. 141430 65 1, is an orally bioavailable antimitotic sulfonamide. ABT 751 binds to the colchicine binding site on beta tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication. This agent also disrupts tumor neovascularization, reducing tumor blood flow and so inducing a cytotoxic effect. Product information CAS Number: 141430 65 1 Molecular Weight: 371. 41 Formula: