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H3B-6545 PEG1-acid CGP77675 dose dependently inhibits phosphorylation

SKU: 51303907888

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Description

CGP77675 dose dependently inhibits phosphorylation of poly-Glu-Tyr with an IC50 value of 5

37)/b8-4-/t21-

and metabolism

2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS)

InChiKey: MTAJESLOWNUVMU-UHFFFAOYSA-N

H3B-6545 PEG1-acid CGP77675 dose dependently inhibits phosphorylationH3B 6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER positive, HER2 negative breast cancer. Product information CAS Number: 2052130 80 8 Molecular Weight: 567. 58 Formula: C30H29F4N5O2 Chemical Name: (2E) N,N dimethyl 4 {[2 ({5 [(1Z) 4,4,4 trifluoro 1 (3 fluoro 2H indazol 5 yl) 2 phenylbut 1 en 1 yl]pyridin 2 yl}oxy)ethyl]amino}but 2 enamide Smiles: CN(C)C(=O) C=C CNCCOC1=CC=C(C=N1) C(=C(

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