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2CH4O3S/c1-3-13-29-24-31-25(30-14-4-2)33-26(32-24)35-17-15-34(16-18-35)23(19-5-9-21(27)10-6-19)20-7-11-22(28)12-8-20
Like other topical corticosteroids
also known as RDEA119
C2HF3O2/c1-38(2)55(65(109)92-50(67(111)112)35-39-14-4-3-5-15-39)94-62(106)49(36-54(75)99)91-63(107)51(37-96)93-61(105)48(34-40-22-24-41(97)25-23-40)90-59(103)45(19-11-31-83-69(78)79)86-57(101)44(18-10-30-82-68(76)77)87-60(104)46(26-27-53(74)98)88-64(108)52-21-13-33-95(52)66(110)47(20-12-32-84-70(80)81)89-58(102)43(17-7-9-29-72)85-56(100)42(73)16-6-8-28-71
Treatment with 3-Oxo-5β-cholanoic acid significantly reduced the activity of the RORγt reporter
TAK-915 melittoside 2CH4O3S/c1-3-13-29-24-31-25(30-14-4-2)33-26(32-24)35-17-15-34(16-18-35)23(19-5-9-21(27)10-6-19)20-7-11-22(28)12-8-20TAK 915 is a potent, selective, brain penetrant and orally active phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0. 61 nM. TAK 915 is >4100 fold more selectivity for PDE2A than PDE1A. TAK 915 has the potential for neuropsychiatric and neurodegenerative disorders treatment. Product information CAS Number: 1476727 50 0 Molecular Weight: 458. 36 Formula: C19H18F4N4O5 Chemical Name: N [(1S) 1 [3 fluoro 4 (trifluoromethoxy)phenyl] 2 methoxyethyl] 7