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ATX inhibitor 5 20529 1-8 min) can reverse calcium

SKU: 54586235128

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Description

1-8 min) can reverse calcium current (ICa) inhibition by WIN 55212-2 in N18 cells

InChiKey: IFWUBRBMMNTBRZ-UHFFFAOYSA-N

CAS Number: 2446154-84-1

25)/t12-/m0/s1

InChi: InChI=1S/C45H72O17/c1-19(18-56-41-38(54)36(52)33(49)29(16-46)60-41)6-9-27-20(2)31-28(59-27)15-26-24-8-7-22-14-23(10-12-44(22

ATX inhibitor 5 20529 1-8 min) can reverse calciumATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15. 3 nM. ATX inhibitor 5 shows anti hepatofibrosis effects and reduces CCl4 induced hepatic fibrosis level prominently. Product information CAS Number: 2402772 45 4 Molecular Weight: 474. 87 Formula: C22H18ClF3N6O Chemical Name: N' [(1E) (4 chlorophenyl)methylidene] 4 {[3 (trifluoromethyl)phenyl]amino} 5H,6H,7H,8H pyrido[4,3 d]pyrimidine 6 carbohydrazide Smiles:

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