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regulates transcription of MDR (increase
Econazole nitrate is a broad spectrum ketoconazole-like azole based antifungal agent which is also potent against Gram positive bacteria
AZ3451 attenuates chondrocytes apoptosis by activating autophagy in vitro
(2014) ChemMedChem
Formula: C19H19N3O3
SCH772984 cin regulates transcription of MDR (increaseSCH772984 is an potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non BRAF mutant
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