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It inhibits TCF/β-catenin mediated transcription by competing with β-catenin for CBP (CREB binding protein) but not p300 binding with an IC50 of 3 µM
McN-JR 3345
VU041 is only moderately metabolized by cytochrome P450 enzymes and does not appear to be metabolized by esterases
Aegeline also prevents growth block in cells expressing the more toxic A53T α-synuclein mutant
CAS Number: 150-13-0
1, 2-Dioleoyl-sn-glycero-3-phosphocholine Catalog No.:M28267-C It inhibits TCF/β-catenin mediated transcription1,2 Dioleoyl sn glycero 3 phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. Product information CAS Number: 4235 95 4 Molecular Weight: 786. 11 Formula: C44H84NO8P Chemical Name: (2 {[(2R) 2,3 bis[(9Z) octadec 9 enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium Smiles: C[N+](C)(C)CCOP([O ])(=O)OC[C@@H](COC(=O)CCCCCCC
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