PF-00562271 EG5-Tos 41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28

41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28

WIN-55212-2 mesylate inhibition of 50 mm K+-evoked CGRP release is not reversed by antagonists of cannabinoid type 1 (CB1) receptor

8 μM across a selected panel of cancer cell lines

Xiaodan & Wu

(2013) Cell Stem Cell

PF-00562271 EG5-Tos 41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28PF 562271, also known as PF 562, 271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Product information CAS Number: 717907 75 0 Molecular Weight: 507. 49