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mTOR and PI3Kα
It down-regulates CDK4 and cyclin D1 expression while does not effect other CDKs and cyclins
InChiKey: OKUWOEKJQRUMBW-UHFFFAOYSA-N
acts as an inhibitor of ADP/ATP carrier
It is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation (episodic irregular heartbeat originating in the upper chamber of the heart)
AZ-PFKFB3-67 quarterhydrate acarb mTOR and PI3KαAZ PFKFB3 67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. Product information Molecular Weight: 460. 01 Formula: C104H102N20O13 Chemical Name: (2S) N [4 [3 cyano 1 [(3, 5 dimethyl 1, 2 oxazol 4 yl)methyl]indol 5 yl]oxyphenyl]pyrrolidine 2 carboxamide quarterhydrate Smiles: O. CC1=NOC(C)=C1CN1C=C(C#N)C2=CC(=CC=C12)OC1C=CC(=CC=1)NC(=O)[C@@H]1CCCN1.
US$ 184.40
US$ 11.95
US$ 200.00