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InChiKey: IXEPQJQQSLMESJ-UHFFFAOYSA-N
5-tetrahydroxy-6-oxohexanoic acid hydrate
Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents
Formula: C7H16N2O2
Formula: C22H29KO4
α-Guanidinoglutaric Acid rulline InChiKey: IXEPQJQQSLMESJ-UHFFFAOYSA-NGuanidinoglutaric Acid is a novel nitric oxide synthase inhibitor with Ki value of 2. 69 M . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger, and it may suppress convulsions . Guanidinoglutaric Acid (GGA) is a novel nitric oxide synthase inhibitor. GGA was increased in the cobalt induced epileptic focus tissue in the cerebral cortex of cats .
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