R-1479 Size:Solid 2 mg Chemical Name: N-(3-Chloro-1H-indol-7-yl)-1

Chemical Name: N-(3-Chloro-1H-indol-7-yl)-1

Dig Dis Sci

Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90

InChi: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26

CAS Number: 391210-00-7

R-1479 Size:Solid 2 mg Chemical Name: N-(3-Chloro-1H-indol-7-yl)-1R 1479, also known as 4' azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and hepatitis C virus replication in cell culture. R 1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC(50) = 1. 28 microM). The corresponding 5' triphosphate derivative (R1479 TP) is a potent inhibitor of native HCV replicase isolated from replicon cells and of recombinant HCV polymerase (NS5B) mediated RNA synthesis