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Ropivacaine - CAS# 84057-95-4 3173 Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CC

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Description

Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CC

Chemical Name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide hydrochloride

Trigonelline protects the cardiocyte from hydrogen peroxide induced apoptosis in H9c2 cells

This derivative may be stable for long periods of time except at high pH

and DNA fragmentation

Ropivacaine - CAS# 84057-95-4 3173 Smiles: CN([C@H](C[C@@H](OC(C)=O)C1=NC(=CS1)C(=O)N[C@@H](CC1C=CC=CC=1)C[C@H](C)C(O)=O)C(C)C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)[C@@H](C)CCRopivacain is a potent sodium channel blocker and acts as a local anesthetic agent. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two pore domain potassium channel) TREK 1 with an IC50 of 402. 7 M in COS 7 cell's membrane. Ropivacaine is used for the research of regional anesthesia and neuropathic pain management. Product information CAS Number: 84057 95 4

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