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15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G
Pranlukast shows competitive antagonism against the LTC4- and LTD4-induced contractions of guinea pig trachea and lung parenchymal strips with a pA2 range of 7
CAS Number: 145317-11-9
and also increases sub-G0/G1 phase population in TT cell culture in a dose-dependent manner
a component of medium chain triclycerides
TRAM 39 13081 15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a naturalTRAM 39, 2 (2 chlorophenyl) 2, 2 diphenyl acetonitrile, is a potent, synthetic, selective inhibitor of intermediate conductance Ca2+ activated K+channels. TRAM 39 selectively block K Ca3 but do not inhibit other Ca2+ activated K+channels.[1,3] Intermediate conductance Ca2 activated K channels are the product of the IKCa1 genes and are important in regulating the membrane potential of colonic epithelial cells, and lymphocytes. The IKCa1 gene is also
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