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Chemical Name: 4-amino-[2
GANT61 is a small-molecule inhibitor of glioma-associated oncogene 1 (GLI1)- and GLI2-mediated transcription at the nuclear level that exerts its effect by preventing DNA binding
The extent of inhibition therefore correlated well with the expected free Quizartinib plasma levels
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(2007) Chembiochem 8(16):1916-9
O-Desmethyl gefitinib D8 Size:Contact [email protected] for quotation Chemical Name: 4-amino-[2O Desmethyl gefitinib D8 is a deuterium labeled O Desmethyl gefitinib. O Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information Molecular Weight: 440. 93 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 {3 [(2, 2, 3, 3, 5, 5, 6, 6
US$ 129.00
US$ 118.00