PF-915275 Catalog No.:M19929-C InChi: InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7

InChi: InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7

1243244-14-5

is observed at least up to this dose

Liothyronine sodium

13(4):387-403

PF-915275 Catalog No.:M19929-C InChi: InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7PF 915275 is a potent, selective and orally active human 11 hydroxysteroid dehydrogenase type 1 (11HSD1) inhibitor with a Ki of 2. 3 nM and an EC50 of 15 nM (in HEK293 cells). The dose dependent effect of PF 915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively. Product information CAS Number: 857290 04 1 Molecular Weight: 350. 39 Formula: C18H14N4O2S Chemical Name: N (6