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ARN-21934 Size:Contact [email protected] for quotation 5-dihydroxy-2-(methylsulfanyl)oxan-3-yl]oxy}phosphonic acid

SKU: 61523874065

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Description

5-dihydroxy-2-(methylsulfanyl)oxan-3-yl]oxy}phosphonic acid

PROTACs that induce the degradation of an oncogenic tyrosine kinase

InChiKey: HQSBCDPYXDGTCL-UHFFFAOYSA-N

Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

NLRC4-stimulated IL-1β and TNF-α secretion (as activated by Salmonella typhimurium) are not inhibited by MCC950 even at a concentration of 10 µM

ARN-21934 Size:Contact [email protected] for quotation 5-dihydroxy-2-(methylsulfanyl)oxan-3-yl]oxy}phosphonic acidARN 21934 is a potent, highly selective, blood brain barrier (BBB) penetrant inhibitor for human topoisomerase II over . ARN 21934 inhibits DNA relaxation with an IC50 of 2 M as compared to the anticancer agent Etoposide (IC50=120 M). ARN 21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research. Product information CAS Number: 2230854 93 8 Molecular Weight: 360. 46 Formula: C21H24N6 Chemical

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