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induces G0/G1-phase cell cycle arrest by decreasing expression of cyclins and CDKs and increases expression of p21 and p27
PRN1371 presents a unique profile of high biochemical and cellular potency (FGFR1 IC50 = 0
The CARD domain of RIP2 kinase mediates interaction with other CARD-containing proteins
This agent shows a favorable toxicity profile in several aspects: it does not generate reactive oxygen species
LNCaP-LN3 cells) treatment decreases S phase and increases the G1 phase in the cells in a dose-dependent manner
Norcholic acid - CAS# 60696-62-0 uxtecan induces G0/G1-phase cell cycle arrestNorcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine. Product information CAS Number: 60696 62 0 Molecular Weight: 394. 54 Formula: C23H38O5 Chemical Name: (3R) 3 [(1R, 3aS, 3bR, 4R, 5aS, 7R, 9aS, 9bS, 11S,
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