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KN-62 inhibits ATP-stimulated ethidium+ uptake
1-(4-hydroxycyclohexyl)-N-(3-methylbutyl)-2-[[5-[2-(trifluoromethoxy)phenyl]-1H-indazol-3-yl]amino]-
Nazartinib has an OC50 (compound concentration at 50% occupancy) value of 2 and 5 nM on HCC827 and H1975
Shinya Kida
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with a IC50 for these effects of approximately 0
PAT-1251 de dipotassium KN-62 inhibits ATP-stimulated ethidium+ uptakePAT 1251 is a potent, selective and oral lysyl oxidase like 2 (LOXL2) inhibitor, with IC50s of 0. 71 and 1. 17 M for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0. 10, 0. 12, and 0. 16 M, respectively); PAT 1251 is used in the research of fibrotic diseases. Product information CAS Number: 2007885 39 2 Molecular Weight: 399. 34 Formula: C18H17F4N3O3 Chemical Name: (3R,4R) 1 (3 {[4 (aminomethyl) 6
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