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ARS-853 Size:Contact [email protected] for quotation CAS Number: 1620278-72-9

SKU: 6492804388

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Description

CAS Number: 1620278-72-9

InChi: InChI=1S/C27H37N3O7S/c1-18(2)15-30(38(33

Smiles: CC1(C)C2[C@@H](OC(C)=O)C(=O)[C@@]3(C)[C@H]([C@H](OC(=O)C4C=CC=CC=4)[C@]1(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)C1C=CC=CC=1)C1C=CC=CC=1)C=2C)[C@@]1(CO[C@@H]1C[C@H]3O)OC(C)=O

3)15-10(14)13-9-7-5-4-6-8-12/h4-9H2

bone resorption and ovariectomised-induced osteoporosis in mice

ARS-853 Size:Contact [email protected] for quotation CAS Number: 1620278-72-9ARS 853 is a cell active, selective, covalent KRAS G12C inhibitor with an IC50 of 2. 5 M. ARS 853 inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. Product information CAS Number: 1629268 00 3 Molecular Weight: 432. 94 Formula: C22H29ClN4O3 Chemical Name: 1 {3 [4 (2 {[4 chloro 2 hydroxy 5 (1 methylcyclopropyl)phenyl]amino}acetyl)piperazin 1 yl]azetidin 1 yl}prop 2 en 1 one Smiles:

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