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7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide dihydrochloride
Formula: C16H14O3
3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM
and therefore a more thorough evaluation of the role of NaV1
1-2H3/t20-/m1/s1
LP-922761 Size:Contact [email protected] for quotation 7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide dihydrochlorideLP 922761 is a potent, selective and orally active adapter protein 2 associated kinase 1 (AAK1) inhibitor with IC50s of 4. 8 nM and 7. 6 nM in enzyme and cell assays, respectively. LP 922761 also inhibits BMP 2 inducible protein kinase (BIKE) with an IC50 of 24 nM. LP 922761 exhibits no significant activity at cyclin G associated kinase (GAK), opioid, adrenergic 2 or GABAa receptors. Product information CAS Number: 1454808 95 7 Molecular Weight: 410.
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