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Bazedoxifene - CAS# 198481-32-2 t A 5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy)methylphosphonicacid

SKU: 65809643045

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Description

5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy)methylphosphonicacid

1355357-49-1

Ca2+ inhibited the currents induced by 100 microM willardiine by approximately 50%

Stat5 and Erk1/2 in R10 cells

Nucleosides Nucleotides Nucleic Acids

Bazedoxifene - CAS# 198481-32-2 t A 5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy)methylphosphonicacidBazedoxifene, also known as WAY 140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole based ER ligand that binds to both ER (IC50 = 26 nM) and ER (IC50 = 99

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