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Bay 41-4109 (less active enantiomer) Size:Contact [email protected] for quotation InChi: InChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3

SKU: 67265831807

4.2
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Description

InChi: InChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3

NCT-503 exhibits favorable absorption

2 nM in H1993 cells

Smiles: CC(=O)N1CCN(CC1)C1C=CC(=CC=1)OC[C@H]1CO[C@@](CN2C=NC=C2)(O1)C1=CC=C(Cl)C=C1Cl

Testing of INCB024360-analog in mice demonstrated pharmacodynamic inhibition of IDO

Bay 41-4109 (less active enantiomer) Size:Contact [email protected] for quotation InChi: InChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3Bay 41 4109 less active enantiomer shows less activity than Bay 41 4109. BAY 41 4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM. Product information CAS Number: 476617 51 3 Molecular Weight: 395. 76 Formula: C18H13ClF3N3O2 Chemical Name: methyl (6S) 6 (2 chloro 4 fluorophenyl) 2 (3,5 difluoropyridin 2 yl) 4 methyl 1,6 dihydropyrimidine 5 carboxylate Smiles: CC1N=C(N[C@@H](C=1C(=O)OC)C1=CC=C(F)C=C1Cl)C1=NC=C(F)C=C1F

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