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26(1):28-38
and the T1/2 is 4
Chemical Name: 3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
Richards FM
a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia
KN-62 - CAS# 127191-97-3 Catalog No.:M6569-10 26(1):28-38KN62, CAS No. 127191 97 3, is a P2X7R antagonist (hP2X7 IC50 = 51 nM) and Ca2+ calmodulin dependent protein kinase II inhibitor. KN62 inhibits the invasiveness of cancer cells in vitro and in vivo KN62 causes retrograde amnesia in the rat. KN62 attenuates glutamate release by inhibiting voltage dependent Ca(2+) channels. The effect of KN62 on Ca(2+) influx appears to be specific to slowly or non inactivating conductances, and therefore presents KN62