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128(10):4485-4500
5 μM (p=0
induces apoptosis in NSCLC cells
H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18
Verstovsek S
NS-2028 0280 128(10):4485-4500NS 2028 is a potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). It blocks sGC activity in murine cerebellum induced by S nitroso glutathione and NMDA (IC50 values are 17 and 20 nM respectively). NS 2028 also inhibits VEGF induced cGMP accumulation. Product information CAS Number: 204326 43 2 Molecular Weight: 269. 05 Formula: C9H5BrN2O3 Synonym: NS 2028 NS2028 Chemical Name: 8 bromo 4H [1, 2, 4]oxadiazolo[3, 4 c][1, 4]benzoxazin 1 one
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