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CWHM-1008 Size:10mg solid Upon hydrolysis intracellularly by esterases

SKU: 70204972308

4.4
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Description

Upon hydrolysis intracellularly by esterases

Steiner MR

PR-39 (100 nM) blocks TNF-α-induced (1 ng/mL

Smiles: ClC1=CN=C(C=C1)N/N=C(/C1=CC=CC=N1)\C1C=CC=CC=1

InChiKey: MEPNHSOMXMALDZ-UHFFFAOYSA-N

CWHM-1008 Size:10mg solid Upon hydrolysis intracellularly by esterasesCWHM 1008 is a potent and orally active antimalarial agent, with EC50 values of 46 and 21 nM against drug sensitive Plasmodium falciparum 3D7 and drug resistant Dd2 strains, respectively. Product information CAS Number: 2362539 97 5 Molecular Weight: 405. 46 Formula: C22H26F3N3O Chemical Name: (3R,4S) N [(1S) 1 [4 (dimethylamino)phenyl]ethyl] 4 [4 (trifluoromethyl)phenyl]pyrrolidine 3 carboxamide Smiles:

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