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TBK1/IKKε-IN-4 ulfonate hydrate) PubMed Central PMCID: PMC4003123

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Description

PubMed Central PMCID: PMC4003123

CAS Number: 1539080-27-7

characterized

23)24)15(8-25)27-9-11/h2-3

Z-VAD(OH)-FMK

TBK1/IKKε-IN-4 ulfonate hydrate) PubMed Central PMCID: PMC4003123TBK1 IKK IN 4 is a 6 aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKK inhibitor with IC50 values of 13 nM and 59 nM, respectively. TBK1 IKK IN 4 shows 100 to 1000 fold less activity against other protein kinases including PDK1, PI3K family members and mTOR. Product information CAS Number: 1381930 17 1 Molecular Weight: 533. 62 Formula: C28H35N7O4 Chemical Name: N {3,4 dimethoxy 5 [3 (4 methylpiperazin 1 yl)propoxy]phenyl} 1 (4

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