5-BDBD Catalog No.:M20319-C Smiles: CC1(C)C[C@H]2C3=CC[C@H]4[C@@](C)(CC[C@H]5[C@@](C)([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)C[C@@]54C)C(O)=O)[C@@]3(CC[C@]2(CC1)C(=O)O[C@@H]1O[C@H](C)[C@H](OC(=O)/C=C/C2C=CC(=CC=2)OC)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O[C@@H]2OC[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)CO

Name: 5-BDBD Catalog No.:M20319-C Smiles: CC1(C)C[C@H]2C3=CC[C@H]4[C@@](C)(CC[C@H]5[C@@](C)([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)C[C@@]54C)C(O)=O)[C@@]3(CC[C@]2(CC1)C(=O)O[C@@H]1O[C@H](C)[C@H](OC(=O)/C=C/C2C=CC(=CC=2)OC)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O[C@@H]2OC[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)CO
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Description

Smiles: CC1(C)C[C@H]2C3=CC[C@H]4[C@@](C)(CC[C@H]5[C@@](C)([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)C[C@@]54C)C(O)=O)[C@@]3(CC[C@]2(CC1)C(=O)O[C@@H]1O[C@H](C)[C@H](OC(=O)/C=C/C2C=CC(=CC=2)OC)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O[C@@H]2OC[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)CO

N[C@H]1CN(CCCC1)C1=C(F)C=C2C(=C1Cl)N(C=C(C(O)=O)C2=O)C1CC1

23)/b4-2+/t11-

ML264 is highly active (IC50=29 nM is a cell-based assay for proliferation of DLD-1 cells

13(2):213-23

5-BDBD Catalog No.:M20319-C Smiles: CC1(C)C[C@H]2C3=CC[C@H]4[C@@](C)(CC[C@H]5[C@@](C)([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)C[C@@]54C)C(O)=O)[C@@]3(CC[C@]2(CC1)C(=O)O[C@@H]1O[C@H](C)[C@H](OC(=O)/C=C/C2C=CC(=CC=2)OC)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O[C@@H]2OC[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)CO5 BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R mediated currents, with an IC50 of 0. 75 M. 5 BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG). Product information CAS Number: 768404 03 1 Molecular Weight: 355. 19 Formula: C17H11BrN2O2 Chemical Name: 10 (3 bromophenyl) 8 oxa 11,14 diazatricyclo[7. 5. 0. 0,]tetradeca 1(9),2,4,6,10 pentaen 13 one Smiles:

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