Pay in 4 interest-free payments of $12.00 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
CAS Number: 121345-64-0
Abemaciclib inhibits the proliferation of the parental A375 and resistant A375RV1 and A375RV2 cells with similar potencies with IC50 values of 395
(2010) Probe Reports from the NIH Molecular Libraries Program
The anticonvulsant effect of WIN-55212-2 mesylate
InChi: InChI=1S/C18H14N2O4/c21-16-9-13(17(22)23)8-15(10-16)20-18(24)19-14-6-5-11-3-1-2-4-12(11)7-14/h1-10
CCF-642 - CAS# 346640-08-2 size:2mg solid CAS Number: 121345-64-0CCF 642, CAS No. 346640 08 2, is a protein disulfide isomerase (PDI) inhibitor. CCF642 exhibited a submicromolar IC50 in 10 of 10 multiple myeloma cell lines. In vitro, CCF642 inhibited PDI reductase activity about 100 fold more potently than the structurally distinct established inhibitors PACMA 31 and LOC14. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL KaLwRij mice