![Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside 2-dihydroisoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]-1H-pyrazole-4-carboxamide](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M31971_1636089156.gif?v=1653631619)
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2-dihydroisoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]-1H-pyrazole-4-carboxamide
Smiles: CCCCCC/C=C/CCCCCCCC(O)=O
Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
is a potent inhibitor of BET bromodomains
falciparum with IC50s of 1
Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside 2-dihydroisoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]-1H-pyrazole-4-carboxamideItraconazole d5 (R51211 d5) is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14 demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Product information CAS
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