![Ro 48-8071 viol Chemical Name: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol hydrochloride](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11212_1621563177.gif?v=1621563179)
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Chemical Name: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol hydrochloride
Epub 2013 Feb 26
InChi: InChI=1S/C30H31FN2O
PubMed PMID: 19648907
note deltorphin I and deltorphin II are available
Ro 48-8071 viol Chemical Name: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol hydrochlorideRo 48 8071 is an orally active cholesterol synthesis inhibitor or a 2,3 oxidosqualene: lanosterol cyclase (OSC) inhibitor. OSC (EC 5. 4. 99. 7) represents a unique target for a cholesterol lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG CoA reductase expression, generating a synergistic, self limited negative regulatory loop.
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