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TCN238 is an orally bioavailable mGlu4 receptor positive allosteric modulator (PAM) with an EC50 of 1 μM
daily for 14 days) potentiates the antitumour activity of CDDP and Cyclophosphamide in nude mice bearing human FaDu and A253 head and neck xenografts
27 March 1998
Formula: C22H24ClN5O2
L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress
ARCC-4 hydrate phen (dihydrochloride monohydrate) TCN238 is an orally bioavailableARCC 4 is a low nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. ARCC 4 inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Product information Molecular Weight: 1042. 19 Formula: C53H58F3N7O8S2 Chemical Name: (2S,4R) 1 [(2S) 2 (2 {4 [(4' {3 [4 cyano 3
US$ 7704.00
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