Mutated EGFR-IN-2 - CAS# 2050906-97-1 Size:Contact [email protected] for quotation Chemical Name: N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-{4-methoxy-1H-pyrrolo[2

Chemical Name: N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-{4-methoxy-1H-pyrrolo[2

Formula: C24H32O4

RNA-binding protein necessary for virus replication

as well as activation of STAT3 and ERK1/2 with IC50 of 60 nM and 62 nM

Chemical Name: (3S

Mutated EGFR-IN-2 - CAS# 2050906-97-1 Size:Contact [email protected] for quotation Chemical Name: N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-{4-methoxy-1H-pyrrolo[2Mutated EGFR IN 2 (compound 91) is a mutant selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single mutant EGFR (T790M) and double mutant EGFR (including L858R T790M (IC50=1nM) and ex19del T790M), and can suppress activity of single gain of function mutant EGFR (including L858R and ex19del) as well. Mutated EGFR IN 2 shows anti tumor antivity. Product information CAS Number: 2050906 97 1 Molecular Weight: 562. 64