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LFM-A13 (200 μM) markedly increases the chemosensitivity of ALL-1 cells to ceramide-induced apoptosis
484(3):486-492
and enhances F508del-CFTR-mediated chloride transport by approximately 5 fold with EC50 of 0
1186/1479-5876-7-43
RG-7834 R-isomer
Raloxifene Hydrochloride mycin Hydrochloride LFM-A13 (200 μM) markedly increasesRaloxifene, also known as LY 139481, is a selective benzothiophene estrogen receptor modulator (SERM). Raloxifene binds to estrogen receptors (ER) as a mixed estrogen agonist antagonist; it displays both an ER alpha selective partial agonist antagonist effect and a pure ER beta selective antagonist effect. This agent functions as an estrogen agonist in some tissues (bones, lipid metabolism) and as an estrogen antagonist in others (endometrium and
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