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Thomas J Johnson
Chemical Name: 4-[(1E)-{[2-(cyclohexylimino)-4-methyl-2
6-tris(propan-2-yl)phenyl]ethan-1-one
InChi: InChI=1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9
and prolongs phase 3 of the cardiac action potential
NF449 octasodium Size:Contact [email protected] for quotation Thomas J JohnsonNF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0. 28, 0. 69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gs selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[S] binding to Gs s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of adrenergic receptors to Gs. Product information CAS Number: 627034 85 9 Molecular Weight: 1505. 09 Formula:
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