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Thalidomide-NH-C6-NH-Boc e-amino-PEG3-NH2 hydrochloride Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1

SKU: 7881062149

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Description

Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1

InChi: InChI=1S/C27H35N3O6S/c1-3-35-26(33)21(28)15-16-23(31)29-22(18-37-17-19-11-7-5-8-12-19)25(32)30-24(27(34)36-4-2)20-13-9-6-10-14-20/h5-14

0001) at concentrations from 1 to 100 μM

and also regulates host immune response

Treatment of primary colorectal cancer xenografts with the small-molecule BMI-1 inhibitor PTC-209 resulted in colorectal CIC loss with long-term and irreversible impairment of tumor growth

Thalidomide-NH-C6-NH-Boc e-amino-PEG3-NH2 hydrochloride Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1Thalidomide NH C6 NH Boc is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used for MI 389 (compound 22) synthesis. MI 389 is a potent phthalimide PROTAC degrader based on the multi targeted receptor tyrosine kinase inhibitor sunitinib (HY 10255A). Product information CAS Number: 2093536 13 9 Molecular Weight: 472. 53 Formula: C24H32N4O6 Chemical Name: tert butyl N (6 {[2 (2,6

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