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InChiKey: RITAVMQDGBJQJZ-FMIVXFBMSA-N
2-a]pyrazin-8-amine
InChi: InChI=1S/C20H17FN2O3S/c1-14-12-16(15-8-4-2-5-9-15)13-18(19(14)21)20(24)22-23-27(25
6 μM and 65 μM for hCyh1
ALK5 and ALK7 (IC50≥500 nM)
Sunitinib D10 fenone D7 Hydrochloride InChiKey: RITAVMQDGBJQJZ-FMIVXFBMSA-NSunitinib D10 (SU 11248 D10) is a deuterium labeled Sunitinib. Sunitinib is a multi targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFR, respectively. Sunitinib, an ATP competitive inhibitor, effectively inhibits autophosphorylation of Ire1 by inhibiting autophosphorylation and consequent RNase activation. Product information CAS Number: 1126721 82 1 Molecular Weight: 408. 54 Formula: C22H27FN4O2 Chemical
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