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Inhibition of intracellular Ca2+ release by a Rho-kinase inhibitor for the treatment of ischemic damage in primary cultured rat hippocampal neurons
57 mg/mL (96
InChi: InChI=1S/C60H83N7O10/c1-41(19-17-20-42(2)39-52(69)70)28-29-48-43(3)49(30-31-60(48
Chemical Name: {6-[2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}amino)-5-fluoropyrimidin-4-yl]-4-fluoro-1-(propan-2-yl)-1H-1
SCC-25 and mouse WEHI-3 cancer cell lines
Estradiol 17-(β-D-Glucuronide) (sodium salt) glumine) Inhibition of intracellular Ca2+ releaseKm: 75 M Estradiol 17 ( D Glucuronide) is a substrate of the multidrug resistance protein 2 (MRP2). MRP2 is a member of the superfamily of ATP binding cassette (ABC) transporters, which transport various molecules across extra and intra cellular membranes. MRP2 is a member of the MRP subfamily that is involved in multi drug resistance. MRP2 is expressed in the apical side of the hepatocyte and functions in biliary transport. In vitro: Estradiol 17 ( D
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