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highly potent and selective BMP pathway inhibitor by inhibiting BMP type I receptors ALK2 (IC50=5 nM) and ALK3 (IC50=30 nM)
Smiles: CC1(C)CC2=CC(OC)=C(C=C2C2=CC3=NC4=CC=CC=C4N=C3N12)OC
Chemical Name: N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]-2-(naphthalen-1-yl)acetamide
IU1 reduces accumulation of oxidized proteins in HEK293 cells
2006 Jan 6
Pemetrexed (disodium hemipenta hydrate) (1:2:2.5) - CAS# 357166-30-4 Catalog No.:M9732-10 highly potent and selective BMPPemetrexed Disodium Hydrate (LY 231514) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1. 3 nM, 7. 2 nM and 65 nM, respectively. Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis. Product information CAS Number: 357166 30 4 Molecular Weight: 1032. 83 Formula: C40H48N10Na4O17 Synonym: Pemetrexed sodium hydrate (1: 2: 2. 5) Chemical Name: tetrasodium bis((2S) 2 {[4 (2 {2 amino 4 oxo 3H,4H,7H pyrrolo[2,3
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