Bromfenac sodium hydrate Size:Contact [email protected] for quotation 3R)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide

3R)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide

It has an IC50 of ~99 nM in inhibiting Myc expression in MV4-11 cells and an IC50 of ~30 nM in inhibiting IL-6 production in THP-1 cells stimulated with LPS

Chemical Name: N-[(5-chloro-2-propoxyphenyl)methyl]-N-(2-{4-[(prop-2-yn-1-yl)sulfamoyl]phenyl}ethyl)-2-(thiophen-3-yl)acetamide

and achieves complete and long-lasting tumor regression in mouse tumor models

6 nM and 665

Bromfenac sodium hydrate Size:Contact [email protected] for quotation 3R)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamideBromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is a potent and orally active inhibitor of COX, with IC50s of 5. 56 and 7. 45 nM for COX 1 and COX 2, respectively. Bromfenac sodium hydrate is a brominated non steroidal anti inflammatory analgesic drug (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME). Product information