Udenafil - CAS# 268203-93-6 119 3-benzothiadiazol-4-amine

3-benzothiadiazol-4-amine

128(2):357-64

Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90

Formula: C38H54N6O11S

Osimertinib was approved in Nov

Udenafil - CAS# 268203-93-6 119 3-benzothiadiazol-4-amineUdenafil is an inhibitor of phosphodiesterase 5 (PDE5). In vivo, udenafil increases lung cGMP levels, attenuates the development of compensatory right ventricular hypertrophy, and reduces pulmonary arterial wall thickening. It increases creatine clearance and decreases blood urea nitrogen (BUN) and serum malondialdehyde (MDA) levels in a rat model of renal ischemia reperfusion injury. Udenafil also induces penile erections in conscious rabbits and in