ARC 239 dihydrochloride 98198 Smiles: CC(C)C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1Cl)B1OC(CC(O)=O)(CC(O)=O)C(=O)O1

Smiles: CC(C)C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1Cl)B1OC(CC(O)=O)(CC(O)=O)C(=O)O1

2000 Mar 20

Formula: C7H16O4

Formula: C9H14N4O2

CAS Number: 2231098-99-8

ARC 239 dihydrochloride 98198 Smiles: CC(C)C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1Cl)B1OC(CC(O)=O)(CC(O)=O)C(=O)O1ARC 239 dihydrochloride is a selective antagonist of 2B adrenoceptor with pKD value of 8. 8 . 2B adrenoceptor is a G protein coupled receptor. 2 adrenergic receptors include three subtypes: 2A, 2B and 2C, which play an important role in regulating neurotransmitter release from adrenergic neurons in the central nervous system and from sympathetic nerves. ARC 239 dihydrochloride is a selective 2B adrenoceptor antagonist. In rat brain, ARC 239 inhibited